Tag: WHO

  • WHO discontinues trial of hydroxychloroquine treatment for COVID-19 patients

    WHO discontinues trial of hydroxychloroquine treatment for COVID-19 patients

    The World Health Organisation (WHO) says it has discontinued the use of hydroxychloroquine and lopinavir/ritonavir in its global trial for treatment of COVID-19 as recommended by the Solidarity Trial’s International Steering Committee.

    The UN health agency, in a statement posted on its website, stated that the Solidarity Trial was established by WHO to find an effective COVID-19 treatment for hospitalised patients.

    “The committee formulated the recommendation in light of the evidence for hydroxychloroquine vs standard-of-care and for lopinavir/ritonavir vs standard-of-care from the Solidarity trial interim results.

    “The trial interim results and from a review of the evidence from all trials presented at the July 1 to July 2, WHO Summit on COVID-19 research and innovation.

    “These interim trial results show that hydroxychloroquine and lopinavir/ritonavir produce little or no reduction in the mortality of hospitalised COVID-19 patients when compared to standard of care.

    “Solidarity trial investigators will interrupt the trials with immediate effect,’’ it said.
    According to the statement, for each of the drugs, the interim results do not provide solid evidence of increased mortality.

    “There were, however, some associated safety signals in the clinical laboratory findings of the add-on Discovery trial, a participant in the Solidarity trial.

    “These will also be reported in the peer-reviewed publication.

    “This decision applies only to the conduct of the Solidarity trial in hospitalised patients and does not affect the possible evaluation in other studies of hydroxychloroquine or lopinavir/ritonavir in non-hospitalised patients or as pre- or post-exposure prophylaxis for COVID-19.

    “The interim Solidarity results are now being readied for peer-reviewed publication.’

  • WHO warns Nigeria, others on scheduled flight resumption

    WHO warns Nigeria, others on scheduled flight resumption

    Ahead of the reopening of airports for the resumption of flights, the World Health Organization (WHO) has urged Nigeria and other African nations to take effective measures to mitigate the risk of a surge in coronavirus infections.

    The global health body said while the opening of borders is vital for the free flow of goods and people, its initial analysis found that lockdowns along with public health measures reduced the spread of COVID-19.

    It said even with border restrictions, imported cases have sometimes brought back COVID-19 to countries which had not reported cases for a length of time.

    The WHO Regional Director for Africa, Mrs Matshidiso Moeti, noted that, “Air travel is vital to the economic health of countries. But as we take to the skies again, we cannot let our guard down. Our new normal still requires stringent measures to stem the spread of COVID-19.”

    This is particularly key for Nigeria and other African nations who are set to restart commercial flights this month.

    On Nigeria’s part, which banned international flights into the country on March 21, it noted that domestic flights between Lagos and Abuja will resume on Wednesday, July 8.

    Domestic flights from Kano, Port Harcourt, Owerri, and Maiduguri airports will reopen on July 11, and all other airports in the country will resume domestic travel from July 15.

    There is, however, no news on international travel, but the Minister for Aviation, Mr Hadi Sirika, said that the date will be decided soon.

    Since its first case in late February 2020, Nigeria has confirmed over 27,000 cases of the virus in the country. For over a month, Lagos, Abuja and Ogun State were completely locked down to curb the contagion.

    The strategy worked in containing the virus, but cries from citizens forced the government to ease the restrictions and since then, there has been a spike in the number of infections.

  • ASUU President states position on reopening of schools

    The Academic Staff Union of Universities (ASUU) on Monday kicked against the reopening of schools by the Federal Government due to the COVID-19 pandemic currently ravaging the country.

    Prof. Biodun Ogunyemi, ASUU National President, who spoke in Ota, Ogun State, said, the Federal Government needed to address the challenges of education sector before it can talk of reopening schools.

    He urged the Federal Government to provide ideal environment and should take the lead by meeting the conditions spelt out by the Nigeria Centre for Disease Control (NCDC) before reopening schools.

    “The Federal Government must lead and show the ways by meeting the conditions for reopening of schools before any school can be allowed to open, because COVID-19 pandemic is a health challenge.

    “When it comes to public health, it is something that should not be left in the hands of individual, but the Federal Government must take the lead,’’ he told NAN.

    The ASUU president listed the conditions spelt out by NCDC to include: provision of materials for regular washing of hands, face mask, isolations centres, space for social distancing and hands sanitiser.

    Ogunyemi said that many of the schools do not have financial capacities to meet those conditions and requirements for reopening of schools.

    “It is suicidal to reopen schools now, if the Federal Government itself could not meet the conditions spelt out by NCDC and World Health Organisation (WHO).

    “The nation will expose the innocent children to risks which is avoidable,” he said.

    Ogunyemi noted that how many of these schools could afford to provide hand sanitiser, saying that many of them do not even have running water, not to talk of having facility for washing hands.

    He added that many schools do not have enough spaces to promote physical distancing.

    The ASUU president said that putting all these requirements needed together, to reopen schools in the country now would run to millions of Naira, which most schools could not afford.

    Ogunyemi appealed to the Federal Government to provide the running funds for the principals and head teachers so that they could provide some of these facilities in their schools.

    He further said that inadequate funds by many parents would hinder them from providing some of these amenities needed for reopening of schools.

    Ogunyemi said that the Federal Government needed to tell Nigerians the steps they intended to take in reopening schools.

    The ASUU leader said that for government not to tell people their minds was like running away from “our shadow” which would later hunt the country.

  • Over $30bn needed to develop COVID-19 tests, treatments, vaccines, says WHO

    Over $30bn needed to develop COVID-19 tests, treatments, vaccines, says WHO

    The World Health Organization said Friday that a global initiative to speed up the development and production of COVID-19 tests, vaccines and treatments will require more than $30 billion over the next year.

    Providing details of the so-called ACT accelerator, launched in April and aimed at pooling international resources to combat the pandemic, WHO said “the costed plans presented today call for $31.3 billion in funding”.

    So far, $3.4 billion of that had been pledged, the UN health agency said, pointing out that an additional $27.9 billion was needed over the next 12 months, including nearly $14 billion to cover immediate needs.

    The announcement came ahead of a major pledging event in Brussels in support of the ACT accelerator, set to take place on Saturday.

    “This is an investment worth making,” Ngozi Okonjo-Iweala, a special envoy for the ACT accelerator, told a virtual briefing.

    “If we don’t rally now, the human costs and the economic pain will deepen,” she said.

    “Though these numbers sound big, they are not when we think of the alternative. If we spend billions now, we will be able to avoid spending trillions later.

    “The time to act is now, and the way to act is together,” the former Nigerian finance minister said, stressing the need for equal access for all to any safe and effective vaccines and treatments developed.

    – ‘Unprecedented speed’ –

    Her comments came as the world counts nearly 490,000 deaths from COVID-19 and over 9.6 million cases since the new coronavirus emerged in China late last year, according to an AFP tally from official sources.

    “It’s clear that to bring COVID-19 under control, and to save lives, we need effective vaccines, diagnostics and therapeutics, in unprecedented quantities and at unprecedented speed,” WHO chief Tedros Adhanom Ghebreyesus told the briefing.

    He stressed though that a core principle of the initiative is to ensure equal access for all.

    “Vaccines, diagnostics and therapeutics are vital tools,” he said.

    “But to be truly effective they must be administered with another essential ingredient, which is solidarity.”

    The funds requested should make it possible to deliver 500 million tests and 245 million courses of treatment to low and middle-income countries by mid-2021.

    They also aim to deliver two billion vaccine doses by the end of next year.

    Soumya Swaminathan, the WHO’s chief scientist, pointed out during a separate briefing on the vaccine pillar of the project, known as COVAX, that antibody studies indicate that “a large, large proportion of the world’s population, 90 percent, continues to be susceptible.”

    “The best bet we have really if we are going to end it… is to have a vaccine as soon as possible.”

    – Vaccinate the most vulnerable –
    There are currently around 220 vaccine candidates, with 15 in clinical trials, and experts are hoping a handful of them will prove successful.

    The problem is that investing in vaccine development can be risky, since 80 percent of vaccines in early stage development fail before reaching clinical trials.

    And since there will be a need to produce billions of doses quickly, manufacturing capabilities need to be scaled up before it is even clear whether a candidate will be successful.

    To address this obstacle, COVAX is aimed at pooling financial and scientific resources, making it possible to hedge the risk of backing an unsuccessful candidate, and ensuring that lower-income countries receive equal access to successful vaccines.

    “The critical issue (is) speed. If we lose a month now, that could mean 200 million fewer doses in 2021,” Seth Berkley, head of the Gavi Vaccine Alliance, told reporters.

    Even producing two billion vaccine doses by the end of 2021 will be far from enough to vaccinate everyone.

    Experts therefore insist on the need to guarantee that vulnerable groups and health workers worldwide receive the first jabs.

    “Having a subset of populations of high risk vaccinated around the world is the best way to control the pandemic,” Berkley said.

  • WHO declares Nigeria polio-free

    WHO declares Nigeria polio-free

    The World Health Organisation (WHO) has declared Nigeria free of wild polio.

    The declaration followed the completion of documentation for the free status.

    WHO regional office for Africa in Brazzaville, Congo, announced this Thursday.

    “Today, Nigeria’s complete documentation for Wild Polio virus free status was accepted by the Africa Regional Certification Commission for polio eradication (ARCC).

    “It is a historic day for Nigeria, Africa and the Global Polio Programme,’’ WHO said.

    Meanwhile, Dr Faisal Shuaib, Executive Director and CEO of the National Primary Health Care Development Agency (NPHCDA), in a tweet at @drfaisalshuaib described the documentation as historic.

    “Amazing moment in history to have had our polio-eradication documentation accepted by (ARCC); the Nigeria team led by NPHCDA and partners demonstrated evidence of our polio-free status.

    “Nigeria achieving a Wild Polio Virus-free status today, is significant on multiple fronts.

    “I look back at the incredible leadership that has brought us here.

    “Apart from President Muhammadu Buhari, GCFR, the two most important people who have made it possible due to their financial and technological contributions have been Mr Aliko Dangote and Mr Bill Gates.

    “Thanks for this unquantifiable gift to Nigeria,’’ he said.

  • WHO okays dexamethasone for treatment of COVID-19

    WHO okays dexamethasone for treatment of COVID-19

    The World Health Organization (WHO) has welcomed the initial clinical trial results from the United Kingdom (UK) that show dexamethasone, a corticosteroid, can be lifesaving for patients who are critically ill with Coronavirus disease (COVID-19).

    TheNewsGuru.com (TNG) reports Fadela Chaib, Communications Officer and Spokesperson of the WHO made this known in a statement on Tuesday, stressing that dexamethasone benefit was only seen in patients seriously ill with COVID-19, and was not observed in patients with milder disease.

    According to preliminary findings shared with WHO, for patients on ventilators, the treatment was shown to reduce mortality by about one third, and for patients requiring only oxygen, mortality was cut by about one fifth.

    “This is the first treatment to be shown to reduce mortality in patients with COVID-19 requiring oxygen or ventilator support. This is great news and I congratulate the Government of the UK, the University of Oxford, and the many hospitals and patients in the UK who have contributed to this lifesaving scientific breakthrough,” Dr Tedros Adhanom Ghebreyesus, WHO Director-General said.

    TNG reports dexamethasone is a steroid that has been used since the 1960s to reduce inflammation in a range of conditions, including inflammatory disorders and certain cancers.

    It has been listed on the WHO Model List of Essential Medicines since 1977 in multiple formulations, and is currently off-patent and affordably available in most countries.

  • Clinical trials underway to evaluate plasma of COVID-19 recovered patients – WHO

    Clinical trials underway to evaluate plasma of COVID-19 recovered patients – WHO

    The World Health Organisation (WHO) says clinical trials are underway to evaluate the effectiveness of using plasma from the blood of recovered COVID-19 patients to reduce the severity of illness among people infected with the virus.

    WHO Regional Director for Africa, Dr Matshidiso Moeti said this in her message to mark the 2020 World Blood Donor Day (WBDD).

    WBDD is celebrated every June 14, to raise awareness on the need for safe blood and blood products, and to thank blood donors for their life-saving gifts of blood.

    “This approach was used by Guinea in the Ebola epidemic in 2014, prior to the availability of Ebola vaccines and therapies.

    “In Mauritius, 150 people who have recovered from COVID-19 have indicated they are willing to give plasma in line with the national decision to use serum plasma therapy for COVID-19 patients in intensive care.

    “The biggest challenge with this approach in many African countries is the insufficient resources of national blood services to safely collect, process and store COVID-19 convalescent plasma in a quality-assured manner.

    “However, the current pandemic is also an opportunity to improve this situation. Kenya, for instance, has allocated a portion of funding from the World Bank specifically to improving blood services during the pandemic,’’ Moeti said.

    In the COVID-19 pandemic, she said the supply of safe blood was at risk, saying: “regular blood donation drives are being postponed, and stay-at-home orders and fear of infection are preventing donors from accessing services.

    “Disruptions to the global supply chain also put countries at risk of shortages of critical supplies and equipment needed for blood donation and transfusion.’’

    According to her, universal access to safe blood is a key component of a resilient health system and contributes to achieving universal health coverage.

    “In the African Region, countries are making progress in improving access to quality-assured blood and blood products.

    “In 2019, eight countries collected 10 units or more per 1000 population as recommended by WHO and 19 countries reached the target of over 80 per cent voluntary non-remunerated blood donations in line with the regional strategy for blood safety.

    “At WHO, we are also exploring partnerships with Facebook to set-up a regional Blood Donations feature, and 15 countries have expressed interest in piloting this tool.

    “The feature connects blood donors with nearby opportunities to donate in collaboration with approved blood banks.’’

    The regional director, however, urged governments, in collaboration with blood donor associations and non-government organisations, to increase investment in blood transfusion services in line with WHO guidance.

    “I wish to thank all voluntary, unpaid blood donors for the life-saving gifts they offer to communities and all the phlebotomists.

    “I also thank other health workers who contribute to blood donation and transfusion services – because of your commitment, safe blood saves lives,’’ she said.

    According to her, On June 14, every year, the African Region joins the global community in celebrating World Blood Donor Day, because blood donors give the gift of life, and more lives will be saved if more people volunteer to donate blood on a regular basis.

    “This year we are calling on people to “give blood and make the world a healthier place” because by regularly volunteering to donate blood, we can all contribute to solidarity and saving lives.

    “Safe blood is a critical resource in severe infant anaemia, postpartum hemorrhage and trauma care. It is also vital in surgeries and the treatment of malaria, sickle cell disease, thalassemia, inherited blood disorders, and AIDS.’’

  • COVID-19: WHO issues new guidance on homemade face masks

    COVID-19: WHO issues new guidance on homemade face masks

    The World Health Organisation (WHO) has issued a new guidance on homemade or locally-made face masks for prevention of COVID-19.

    The WHO Regional Office for Africa in Brazzaville, Congo, gave the advice on Sunday on its official twitter handle @WHOAFRO.

    The UN health agency urged people to clean locally-made face masks properly before wearing again.

    According to WHO, the guidance on homemade masks are important for preventing COVID-19 in low-income context.

    In a video posted on the twitter account, Guy Mbayo, Technical Officer, Water, Sanitation and Hygiene (WASH), WHO Regional Office for Africa, said homemade masks were important for African countries.

    “WHO has recommended the wearing of medical masks; at the beginning of the crisis, there were not enough; supply chain was already disrupted.

    “Member-states and governments have made wearing of face masks mandatory in their own countries; people were prompted to resort to homemade masks,’’ he said.

    According to him, the document provides guideline on how to wear them; how to clean them; how to remove them and when to remove them, and much more importantly, how to manufacture them locally.

    “The masks do not protect you fully; you still need to observe all the measures that were recommended, like the hand washing with soap and water, and physical distancing.

    “When you are removing the mask, don’t allow it to touch your hand; use the elastic to remove it without touching the mask itself,” he said.

    The official also advised that the masks needed to be clean on a daily basis.

    Meanwhile, the agency said the number of COVID-19 cases in Africa had risen to over 175,000 as at June 6.

    “There are over 175,000 confirmed COVID-19 cases on the African continent, with more than 77,000 recoveries and 4,800 deaths,’’ it said.

    WHO said that South Africa, Nigeria and Algeria had the highest reported cases in the continent.

    According to the organisation, South Africa has 43,434 cases and 908 deaths, followed by Nigeria with 11,844 confirmed cases and 333 deaths, while Algeria has 9,935 confirmed cases and 690 deaths.

  • WHO to resume trial of hydroxycholoroquine on COVID-19

    WHO to resume trial of hydroxycholoroquine on COVID-19

    The World Health Organisation (WHO) says it will resume its trial of hydroxychloroquine for the treatment of coronavirus (COVID-19) patients.

    WHO Director-General, Dr Tedros Ghebreyesus, stated this in official twitter account of the UN health agency.

    According to him, the hydroxychloroquine section of the WHO’s Solidarity Trial can resume after being paused temporarily on May 25.
    The trial’s Data Safety and Monitoring Committee had halted the study as a precaution in response to safety concerns raised by an observational study published in the Lancet.

    Ghebreyesus said the Data Safety Monitoring Board’s review had been completed.

    “Last week, the Executive Group of the Solidarity Trial decided to implement a temporary pause of the hydroxychloroquine arm of the trial, because of concerns raised about the safety of the drug.

    “This decision was taken as a precaution while the safety data were reviewed; the Data Safety and Monitoring Committee of the Solidarity Trial has been reviewing the data.

    “On the basis of the available mortality data, the members of the committee recommended that there are no reasons to modify the trial protocol.

    “The Executive Group received this recommendation and endorsed the continuation of all arms of the Solidarity Trial, including hydroxychloroquine.

    “The Executive Group will communicate with the principal investigators in the trial about resuming the hydroxychloroquine arm,’’ he said.

    The director-general said the Data Safety and Monitoring Committee would continue to closely monitor the safety of all therapeutics being tested in the Solidarity Trial.

    “So far, more than 3,500 patients have been recruited in 35 countries.

    “WHO is committed to accelerating the development of effective therapeutics, vaccines and diagnostics as part of our commitment to serving the world with science, solutions and solidarity,’’ he said.

    Meanwhile, Nigeria, on May 27, declared that it would continue with hydroxychloroquine clinical trials on COVID-19 patients.

    Prof. Mojisola Adeyeye, the Director-General of National Agency for Food and Drug Administration and Control (NAFDAC) said the country would continue with the drug, in spite of the initial warning by WHO to discontinue using it.

    ”I do not know the data that they’re looking at, whether it’s from the Caucasian population or from the African population.

    ”If the data they’re looking at, and the reason for suspending the trials, is from the Caucasian population, then it may be justified.

    “But I don’t think we have data from the African population yet, because our genetic makeup is different.

    ”If medical doctors, research scientists, pharmacists, herbal experts work together, we should conclude the clinical trial in three-four months.

    “The narrative might change afterward but for now, we believe in hydroxychloroquine,” she said.

  • Rising cases of COVID-19 in America worry WHO

    Rising cases of COVID-19 in America worry WHO

    Dr Tedros Ghebreyesus, the Director-General, World Health Organisation (WHO), has expressed worry over the rise of Coronavirus (COVID-19) cases reported in America.

    Ghebreyesus said this at a news conference at WHO headquarters in Geneva.

    According to him, more than 100,000 cases of COVID-19 have been reported to WHO for each of the past five days.

    “The Americas continues to account for the most cases. For several weeks, the number of cases reported each day in the Americas has been more than the rest of the world put together.

    “We are especially worried about Central and South America, where many countries are witnessing accelerating epidemics.

    “We also see increasing number of cases in the Eastern Mediterranean, South-East Asia and Africa, although the numbers are much smaller.”

    Meanwhile, the director general noted that the number of cases in Europe had continued to decline, saying, “we saw the fewest cases reported in Europe since the 22nd of March on Tuesday.

    “WHO continues to work through our regional and country offices to monitor the pandemic, to support countries to respond, and to adapt our guidance for every situation.

    “WHO continues to provide the world with new and updated technical guidance, based on the most up-to-date evidence.

    “Just in the past week, WHO has released a new case report form for suspected cases of multi system inflammatory syndrome in children and operational guidance on maintaining essential health services.

    “We have released guidance on controlling the spread of COVID-19 at ground crossings; planning recommendations for mass gatherings and a protocol for surveillance of infections among health workers.

    “Also, we have released ethical considerations for the use of digital technologies in tracking COVID-19 and updated guidelines on the clinical management of patients with COVID-19.

    “This is an update of the guidance we published in March,’’ he said.

    In addition, Ghebreyesus said the guidance included a COVID-19 care pathway, which described the steps followed by a patient from screening to discharge, to ensure delivery of safe and quality care, while stopping onward transmission.

    “WHO continues to train millions of health workers all over the world to apply our guidance; our OpenWHO.org online learning platform has now registered three million enrollments for our courses on COVID-19.

    “And we have added two new courses: one on decontamination and sterilisation of medical devices and another on environmental cleaning and disinfection.

    “In total, we’re now offering 12 courses in 27 languages; in the past week, we launched COVID-19 courses in Amharic, Arabic, French, Hausa, Macedonian, Odia, Spanish and Vietnamese,’’ he said.

    The director-general further said that WHO would continue to respond to the new Ebola outbreak in the city of Mbandaka, in the Equateur province of the Democratic Republic of the Congo.

    “So far, eight cases have been detected. Four of those have died and the other four are receiving care.

    “To be clear, this outbreak is in the same area as a previous outbreak in 2018, which was stopped in just three months.

    “However, it is on the other side of the country to the Ebola outbreak that WHO and partners have been fighting for almost two years in the provinces of North Kivu and Ituri, in eastern DRC.

    “The latest person confirmed with Ebola attended the burial of one of the first cases, but was detected in the town of Bikoro, 150 kilometres away from Mbandaka. This means that two health zones are now affected,’’ he said.

    According to him, almost 50 responders from WHO and partners arrived in Mbandaka on Wednesday, plus 3,600 doses of Ebola vaccine and 2,000 cartridges for lab testing.

    “The government is now sequencing the virus to see whether or not it is related to a previous outbreak.

    “This is an important reminder that even as WHO focuses on responding to the COVID-19 pandemic, we continue to monitor and respond to many other health emergencies.’’